Thermo Fisher Scientific SHPK Monoclonal Antibody (OTI1D2), TrueMAB
SHPK 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 면역세포염색에 적합. HEK293T 세포에서 발현된 full-length 인간 SHPK 항원을 면역원으로 사용. 친화 크로마토그래피로 정제된 동결건조 형태이며, 보존제 무첨가. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D2 |
| Immunogen | Full length human recombinant protein of human SHPK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The SHPK gene encodes a protein with weak homology to several carbohydrate kinases, which are involved in phosphorylation of sugars as they enter cells. Sequence variations suggest potential differences in substrate specificity or kinetic properties compared to other carbohydrate kinases.
This gene is located in a region often deleted in cystinosis patients, suggesting a possible role as a modifier of the cystinosis phenotype. The genomic region is rich in Alu repetitive sequences, which are frequently associated with chromosomal rearrangements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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