Thermo Fisher Scientific ACY1 Monoclonal Antibody (OTI2F1), TrueMAB
ACY1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, IHC, Flow Cytometry에 사용 가능. 인간 및 개 시료 반응성. Lyophilized 형태로 제공되며, PBS 버퍼에 8% trehalose 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F1 |
| Immunogen | Full length human recombinant protein of human ACY1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ACY1 encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group. It functions in the catabolism and salvage of acylated amino acids.
Located on chromosome 3p21.1, this gene shows reduced expression in small-cell lung cancer (SCLC). Mutations cause aminoacylase-1 deficiency, a metabolic disorder with CNS defects and increased urinary excretion of N-acetylated amino acids.
Alternative splicing results in multiple transcript variants, and read-through transcription exists between ACY1 and ABHD14A. A related pseudogene is found on chromosome 18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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