Thermo Fisher Scientific SHPK Monoclonal Antibody (OTI3D7), TrueMAB
Human SHPK 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot, IHC, ICC/IF에 사용 가능. Lyophilized 형태로 제공되며, PBS 기반 버퍼에 trehalose 포함. 연구용으로만 사용되며, 안정적 저장 및 재구성 용이.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D7 |
| Immunogen | Full length human recombinant protein of human SHPK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The SHPK gene encodes a protein with weak homology to several carbohydrate kinases, which are involved in phosphorylation of sugars entering cells, preventing their return across the membrane.
Sequence variations suggest differences in substrate specificity or kinetic properties compared to known carbohydrate kinases.
This gene is located in a region commonly deleted in cystinosis patients, potentially acting as a modifier for the cystinosis phenotype.
The genomic region is rich in Alu repetitive sequences, which are often associated with chromosomal rearrangements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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