Thermo Fisher Scientific NLGN4X (Neuroligin-4) Monoclonal Antibody (N98/7), PE
PE 형광 표지된 Neuroligin-4 단클론 항체로, 마우스 및 랫트 시료에 반응합니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능하며, 높은 특이성과 낮은 교차반응성을 제공합니다. 단백질 G 정제, 4°C 보관.
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Thermo Fisher Scientific NLGN4X (Neuroligin-4) Monoclonal Antibody (N98/7), PE
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N98/7 |
| Immunogen | Fusion protein amino acids 782–945 (intracellular C-terminus) of mouse Neuroligin 4 |
| Conjugate | PE |
| Excitation/Emission Max | 565/576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932150 |
Available Formats
Product Specific Information
- ~45% identity with Neuroligin-1, -2, and -3
- 1 µg/mL of MA5-45696 detects Neuroligin 4 in 20 µg of mouse brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody
- Detects approximately 125–130 kDa
- Does not cross-react with other Neuroligins
- Formerly sold as clone S98-7
Target Information
Neuroligin-4, X-linked (NLGN4X) is a postsynaptic cell-adhesion molecule interacting with presynaptic neurexins, bridging the synaptic cleft and playing an essential role in synaptic transmission.
There are five neuroligin genes in humans: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y.
Mutations in NLGN3 and NLGN4X are linked to Autism Spectrum Disorders (ASD).
Expression of NLGN4X has been reported in human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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