Thermo Fisher Scientific NLGN4X (Neuroligin-4) Monoclonal Antibody (N98/7), FITC
FITC로 표지된 Neuroligin-4 단클론 항체로, 마우스 및 랫트 시료에 반응. WB, IHC(P), ICC/IF 등 다양한 응용 가능. 단백질 G로 정제된 액상 형태이며, 보존제 없음. 암실에서 4°C 보관.
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Thermo Fisher Scientific NLGN4X (Neuroligin-4) Monoclonal Antibody (N98/7), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N98/7 |
| Immunogen | Fusion protein amino acids 782–945 (intracellular C-terminus) of mouse Neuroligin 4 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932148 |
Additional Formats
- Unconjugated (MA5-27585)
- APC (MA5-45693)
- PE (MA5-45696)
- PerCP (MA5-45695)
- Request custom conjugation (Thermo Fisher form available)
Product Specific Information
- Approximately 45% identity with Neuroligin-1, -2, and -3
- 1 µg/mL of MA5-45694 detects Neuroligin 4 in 20 µg of mouse brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody
- Detects ~125–130 kDa
- Does not cross-react with other Neuroligins
- Formerly sold as clone S98-7
Target Information
Neuroligin-4, X-linked (NLGN4X, NLGN4, Neuroligin-4, Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic neurexins. These interactions bridge the synaptic cleft and play an essential role in synaptic transmission between neurons.
Humans have five neuroligin genes: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y.
Mutations in NLGN3 and NLGN4X are associated with Autism Spectrum Disorders (ASD).
Expression of Neuroligin-4, X-linked has been reported on human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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