Thermo Fisher Scientific NLGN4X (Neuroligin-4) Monoclonal Antibody (N98/7), PerCP
NLGN4X(Neuroligin-4) 단백질을 특이적으로 인식하는 PerCP 결합 단일클론 항체. 마우스 및 랫트 반응성. WB, IHC, ICC/IF에 사용 가능. 고순도 Protein G 정제, 보존제 없음, 4°C 보관.
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- MA545695
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Thermo Fisher Scientific NLGN4X (Neuroligin-4) Monoclonal Antibody (N98/7), PerCP
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N98/7 |
| Immunogen | Fusion protein amino acids 782–945 (intracellular C-terminus) of mouse Neuroligin 4 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932149 |
Additional Formats
Product Specific Information
- ~45% identity with Neuroligin-1, -2, and -3
- 1 µg/mL of MA5-45695 detects Neuroligin 4 in 20 µg of mouse brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP as secondary antibody
- Detects approximately 125–130 kDa
- Does not cross-react with other Neuroligins
- Formerly sold as clone S98-7
Target Information
Neuroligin-4, X linked (NLGN4X, NLGN4, Neuroligin-4, Neuroligin 4X) is a postsynaptic cell-adhesion molecule that interacts with presynaptic cell-surface neurexins. These interactions bridge the synaptic cleft and play an essential role in synaptic transmission between neurons.
Humans have five neuroligin genes: NLGN1, NLGN2, NLGN3, NLGN4X, and NLGN4Y. Mutations in NLGN3 and NLGN4X are associated with Autism Spectrum Disorders (ASD). Expression of NLGN4X has been reported in human pluripotent stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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