Thermo Fisher Scientific NLGN3 Monoclonal Antibody (N110/29), APC
NLGN3 단백질을 검출하기 위한 Thermo Fisher Scientific의 APC 결합 단일클론 항체. 인간, 생쥐, 랫트 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능. 고순도 Protein G 정제, 4°C 보관. 신경 시냅스 형성 및 자폐 스펙트럼 연구에 적합.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N110/29 |
| Immunogen | Fusion protein amino acids 730–848 (intracellular C-terminus) of rat Neuroligin-3 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932151 |
Additional Formats
- Unconjugated (MA5-27621)
- FITC (MA5-45698)
- PE (MA5-45700)
- PerCP (MA5-45699)
- Custom conjugation available upon request
Product Specific Information
- Mouse: 99% identity (118/119 amino acids identical)
- Human: 98% identity (116/119 amino acids identical)
- ~60% identity with Neuroligin-1; ~40% identity with Neuroligin-2
- 1 µg/mL of MA5-45697 detects Neuroligin 3 in 20 µg rat brain lysate by colorimetric immunoblot using Goat anti-mouse IgG:HRP
- Detects approximately 110 kDa
- No cross-reactivity with Neuroligin-1, -2, -4, or -4
- Formerly sold as clone S110-29
Target Information
This gene encodes a neuronal cell surface protein family member that acts as a splice site-specific ligand for beta-neurexins and may participate in the formation and remodeling of central nervous system synapses. Mutations may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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