Thermo Fisher Scientific Dystrophin Monoclonal Antibody (1808)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

2-4 µg/mL

-

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Product Specifications

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1808

Immunogen

Acetylcholine receptor (AChR)-enriched membranes and peripheral membrane proteins from Torpedo nobiliana electric organ if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Dystrophin,uniProtId:P11532-1,ncbiNodeId:9606,antigenRange:1-3685,antigenLength:3685,antigenImageFileName:MA5-13526_Dystrophin_P11532-1_House_mouse.svg,antigenImageFileNamePDP:MA5-13526_Dystrophin_P11532-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11000900

Product Specific Information

MA5-13526 targets Dystrophin in IF, IHC (P) applications and shows reactivity with Human samples.

The MA5-13526 immunogen is acetylcholine receptor (AChR)-enriched membranes and peripheral membrane proteins from Torpedo nobiliana electric organ.

Target Information

Dystrophin is the 427kDa protein product of the DMB/BMD gene located on the X chromosome at position Xp21. Western blotting and immunohistochemistry are the two established methods for the detection of abnormalities of dystrophin expression in muscle biopsies. Dystrophin abnormalities are thought to occur in 100% of patients with DMD/BMD, although genetic abnormalities may only be detected in up to 65% of cases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.