Thermo Fisher Scientific PDPK1 Polyclonal Antibody
Rabbit polyclonal antibody targeting PDPK1, validated for WB and IHC applications. Recognizes human, mouse, and rat proteins. High purity (>95%) and antigen affinity purified. Ideal for studying kinase signaling and metabolic pathways.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 211–260 of human PDK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553356 |
Product Specific Information
This antibody detects endogenous PDPK1 protein at a molecular weight of approximately 63 kDa.
Purity is >95% by SDS-PAGE.
Target Information
PDPK1 (3-Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases and activates conventional PKC and PKC zeta through phosphorylation of threonine residues in the activation loop.
It also phosphorylates Protein Kinase B (PKB/Akt) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate.
Activated Akt inactivates Glycogen Synthase Kinase 3 (GSK3), leading to activation of glycogen synthase and stimulation of glycogen synthesis.
Because of its role in insulin-induced glycogen synthesis and PKC activation, PDPK1 is an important target for metabolic drug research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific STAT5 alpha/beta Polyclonal Antibody
640,300원
Thermo Fisher Scientific
Thermo Fisher Scientific Sodium Channel Pan Polyclonal Antibody
630,500원
Thermo Fisher Scientific
Thermo Fisher Scientific PDPK1 Polyclonal Antibody
630,500원
Thermo Fisher Scientific
Thermo Fisher Scientific KV3.2 (KCNC2) Polyclonal Antibody
630,500원
Thermo Fisher Scientific
Thermo Fisher Scientific MAGE1 Polyclonal Antibody
630,500원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|