Thermo Fisher Scientific MAGE1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 280-309 of Human MAGE-1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MAGE1,uniProtId:P43355-1,ncbiNodeId:9606,antigenRange:280-309,antigenLength:309,antigenImageFileName:PA5-36063_MAGE1_P43355-1_Rabbit.svg,antigenImageFileNamePDP:PA5-36063_MAGE1_P43355-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2553352

Product Specific Information

This antibody detects endogenous levels of MAGE-1 protein at a molecular weight of 34 and 46 kDa and also detects endogenous levels of Tumor antigen MAGE-N.

Purity is >95% by SDS-PAGE.

Target Information

Human malignant neoplasms carry rejection antigens that are recognized by the patients` autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.