Thermo Fisher Scientific STAT5 alpha/beta Polyclonal Antibody
STAT5 alpha/beta 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간 및 생쥐 반응성. 91 kDa 내인성 단백질 검출. 고순도(>95%) 항원 친화 크로마토그래피 정제. 연구용 한정 제품.
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Thermo Fisher Scientific STAT5 alpha/beta Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 650–700 of human Stat5a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553359 |
Product Specific Information
- Detects endogenous protein at a molecular weight of 91 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases, then form homo- or heterodimers that translocate to the cell nucleus to act as transcription activators.
This protein mediates responses to ligands such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and various growth hormones. Activation of this protein in myeloma and lymphoma with a TEL/JAK2 gene fusion is independent of cell stimulus and essential for tumorigenesis. The mouse counterpart induces expression of BCL2L1/BCL-X(L), suggesting an antiapoptotic role.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-36075_STAT5_alphabeta_P42229-1_Rabbit.svg, PA5-36075_STAT5_alphabeta_P42229-1_Rabbit_PDP.jpeg)
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