Thermo Fisher Scientific CD56 (NCAM) Monoclonal Antibody (TULY56), APC, eBioscience
인간 및 비인간 영장류 CD56(NCAM) 검출용 단클론 항체. Flow Cytometry에 최적화된 APC 형광 표지 제품. NK 및 NKT 세포 분석에 적합하며, 고순도의 액상 형태로 제공. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.125 µg)/test
- View 15 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rhesus monkey |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TULY56 |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573147 |
Available Conjugate Formats
- Alexa Fluor 660, Alexa Fluor 700, APC-eFluor 780
- Brilliant UV 395, 563, 661, 737, 805
- Brilliant Violet 421, 605, 650, 711, 786
- eFluor 450, 506, FITC
- NovaFluor Blue 660-120S, 800
- NovaFluor Red 700, 710, 725
- NovaFluor Yellow 690, 810
- PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
- PerCP-eFluor 710, Super Bright 436, 600, 645, 702, 780
- Request custom conjugation
Product Specific Information
This TULY56 monoclonal antibody reacts with human CD56 (Neural Cell Adhesion Molecule, NCAM), a highly glycosylated transmembrane molecule expressed by neurons, NK cells, and NKT cells. It mediates homotypic adhesion of neural cells.
- Epitope: TULY56 does not block CMSSB binding, indicating distinct epitopes.
- Performance: Performs better after fixation and permeabilization than CMSSB.
- Cross-reactivity: Rhesus macaque.
- Applications Reported: Flow cytometric analysis.
- Applications Tested: Pre-titrated for flow cytometry of normal human peripheral blood cells.
- Use 5 µL (0.125 µg) per test (100 µL final volume).
- Suitable for 10⁵–10⁸ cells/test.
- Excitation: 633–647 nm
- Emission: 660 nm
- Laser: Red Laser
- Filtration: 0.2 µm post-manufacturing filtered.
Target Information
CD56 (NCAM) is a transmembrane glycoprotein of the immunoglobulin family involved in cell adhesion and neural development. It is expressed in the nervous system and on T and NK cells, contributing to cell migration, axonal growth, and synaptic plasticity. Polysialic modification reduces adhesion activity.
CD56 is expressed in neuroectodermal-derived cells and tumors such as retinoblastoma, medulloblastoma, astrocytoma, and neuroblastoma. It is a key neuroendocrine marker with high sensitivity for neuroendocrine and ovarian granulosa cell tumors. CD56 dysfunction is associated with rabies and blastic plasmacytoid dendritic cell neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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