Thermo Fisher Scientific Cytokeratin 6B (KRT6B) (Basal Cell Marker) Monoclonal Antibody (KRT6B/2116)
Basal cell marker로 사용되는 Cytokeratin 6B 단클론 항체로, Mouse/IgG2a isotype을 가지며 Human 및 Mouse 시료에 반응합니다. IHC(P) 및 IHC(PFA) 적용 가능하며, Protein A/G로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT6B/2116 |
| Immunogen | Recombinant full-length human KRT6B protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the keratin gene family. Type II cytokeratins consist of basic or neutral proteins arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues.
Up to six type II cytokeratins (KRT6) have been identified, resulting from successive gene duplication events. These genes are coexpressed with KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and glandular epithelia.
Mutations in these genes are associated with pachyonychia congenita. Type II cytokeratins are clustered in a region of chromosome 12q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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