Thermo Fisher Scientific MPP5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MPP5, validated for WB and IHC. Recognizes amino acids 2–50 of MPP5. Lyophilized, unconjugated form with no preservative. Store at 4°C short term or -20°C long term. For research use only.
- 카탈로그번호
- OSM00124W-100UL
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 2–50 of human MPP5 conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: MPP5.
Target Information
MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis. It is essential for establishing and maintaining cell polarity in epithelial cells and neurons and functions as part of the Par-3 complex to maintain tight junctions.
Mutations in MPP5 are associated with severe neurological impairments, including global developmental delay (GDD) and behavioral changes. In animal models, MPP5 is involved in early differentiation of multipotent progenitors and supports lineage-specific contributions in myeloid and lymphoid cells. MPP5 variants can disrupt normal cellular function, leading to developmental and functional abnormalities.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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