Thermo Fisher Scientific HDAC1 Monoclonal Antibody (CL0510)
HDAC1 단백질을 인식하는 mouse monoclonal antibody(CL0510). Western blot, IHC, ICC/IF에 최적화되어 있으며 Human, Mouse, Rat 시료에 반응. Protein A 정제, PBS/glycerol buffer 저장. 세포 성장 및 분화 연구용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0510 |
| Immunogen | Recombinant protein corresponding to Human HDAC1 (amino acids 413–477) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2848890 |
Product Specific Information
Immunogen sequence:
RIACEEEFSD SEEEGEGGRK NSSNFKKAKR VKTEDEKEKD PEEKKEVTEE EKTKEEKPEA KGVKE
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression.
HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.
It interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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