Thermo Fisher Scientific Phospho-Parkin (Ser101) Polyclonal Antibody
파킨 단백질의 Ser101 인산화 부위를 인식하는 토끼 폴리클로날 항체. Western blot에 적합하며 인간 시료에 반응. 친화 크로마토그래피로 정제된 액상 형태로, 보존제 없이 -20°C에서 보관. 파킨 변이 연구 및 파킨슨병 관련 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser101 of human PARK2 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1090600 |
Product Specific Information
This antibody is predicted to react with bovine and non-human primate based on 100% sequence homology.
Target Information
The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation.
Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease.
Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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