Thermo Fisher Scientific GnRH-Receptor/LH-RH Receptor Monoclonal Antibody (F1G4)
GnRH 수용체를 인식하는 단클론 항체로 Western blot, IHC, ICC, Flow cytometry에 사용 가능. Human 및 Rat 반응성. 단백질 A/G 정제, 액상 형태, 4°C 보관. 연구용으로만 사용.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F1G4 |
| Immunogen | A synthetic peptide aa 1–29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) from the N-terminal of human GnRH receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react with Pig, Rabbit.
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone (GnRH). It belongs to the seven-transmembrane, G-protein coupled receptor (GPCR) family and is expressed on the surface of pituitary gonadotrope cells, lymphocytes, breast, ovary, and prostate. Upon binding of GnRH, the receptor activates a phosphatidylinositol-calcium second messenger system, leading to the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). Mutations in this gene can cause hypogonadotropic hypogonadism (HH). Multiple transcript variants and alternative splicing forms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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