Thermo Fisher Scientific GnRH-Receptor/LH-RH Receptor Monoclonal Antibody (GNRHR/768)
GnRH-Receptor/LH-RH 수용체를 인식하는 Mouse 모노클론 항체로, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 인간 시료 반응성, 고순도 Protein A/G 정제, PBS 기반 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GNRHR/768 |
| Immunogen | Recombinant full-length human GNRHR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone (GnRH). The receptor belongs to the seven-transmembrane, G-protein coupled receptor (GPCR) family and is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate tissues. Upon binding of GnRH, the receptor activates a phosphatidylinositol-calcium second messenger system, leading to the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). Mutations in this gene can cause hypogonadotropic hypogonadism (HH). Multiple transcript variants and alternative splicing have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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