Thermo Fisher Scientific GnRH-Receptor/LH-RH Receptor Monoclonal Antibody (F1G4)
GnRH-Receptor/LH-RH 수용체를 인식하는 단클론 항체로, 인간과 랫트에 반응. WB, IHC, ICC, Flow 등 다양한 응용에 사용 가능. 단백질 A/G로 정제된 액상 형태로, PBS(pH 7.4)에 보존제 없이 제공. 연구용으로만 사용.
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Thermo Fisher Scientific GnRH-Receptor/LH-RH Receptor Monoclonal Antibody (F1G4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F1G4 |
| Immunogen | Synthetic peptide aa 1–29 (MANSASPEQNQHCSAINNSIPLMQGNLPY) from the N-terminal of human GnRH receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react with Pig and Rabbit.
Target Information
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. The receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family and is expressed on pituitary gonadotrope cells, lymphocytes, breast, ovary, and prostate. Upon binding gonadotropin-releasing hormone, the receptor activates a phosphatidylinositol-calcium second messenger system, leading to release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). Mutations can cause hypogonadotropic hypogonadism (HH). Multiple transcript variants exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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