Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (LL002), Biotin
Cytokeratin 14(KRT14) 단백질을 인식하는 LL002 클론의 Biotin 결합 단일클론 항체. 인간, 생쥐, 랫트 반응성. 면역조직화학, 면역형광, 유세포분석 등에 사용 가능. Protein A/G 정제, PBS buffer, 4°C 보관.
- 카탈로그번호
- 3861-MSM1-B1
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LL002 |
| Immunogen | A synthetic peptide of 15 amino acids from the C-terminus of human keratin 14 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, found in both keratinizing (e.g., skin) and non-keratinizing tissues (e.g., mesothelial cells). At least 20 different CKs are identified, generally classified into type I (acidic polypeptides) and type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily and pairs with keratin 5, distinguishing stratified epithelial cells from simple epithelial cells. It serves as a useful marker for squamous cell carcinomas and is considered a prognostic marker in breast carcinomas. Both acidic and basic keratin types are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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