Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (LL002)
사람, 생쥐, 랫트 반응성을 가진 Cytokeratin 14 단클론 항체로, 상피세포 및 편평세포암 표지에 활용 가능. IHC, ICC, Flow Cytometry 등 다양한 응용에 적합하며, 고순도 Protein A/G 정제 및 PBS 버퍼로 안정적 보관 가능.
- 카탈로그번호
- 3861-MSM1-P1ABX
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LL002 |
| Immunogen | A synthetic peptide of 15 amino acids from the C-terminus of human keratin 14 (amino acids 457–472, UniProt ID: P02533-1). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, both keratinizing (e.g., skin) and non-keratinizing (e.g., mesothelial cells). Over 20 CK types have been identified, classified as type I (acidic) and type II (basic) polypeptides.
Keratin 14, a type I low molecular weight keratin, forms complexes with keratin 5 and is characteristic of stratified epithelial cells. It serves as a useful marker for squamous cell carcinomas and is considered prognostic in breast carcinoma.
All epithelial cells express at least one acidic and one basic CK family member.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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