Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (KRT14/6957)
사이토케라틴 14(KRT14)를 인식하는 단클론 항체로, 편평세포 마커로 사용됩니다. 인체 시료에 반응하며 IHC(P) 및 IHC(PFA) 실험에 적합합니다. 단백질 A/G로 정제된 액상 항체로, 보존제가 포함되지 않습니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT14/6957 |
| Immunogen | Recombinant human KRT14 fragment (around aa350–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs can be identified. Most members of the CK family fall into one of two classes:
- Type I (acidic polypeptides)
- Type II (basic polypeptides)
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and exists in combination with keratin 5. It distinguishes stratified epithelial cells from simple epithelial cells and is useful for identifying squamous cell carcinomas. It is also considered a prognostic marker in breast carcinomas. At least one member of the acidic family and one of the basic family are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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