Thermo Fisher Scientific CD20 Monoclonal Antibody (2H7), Alexa Fluor 700, eBioscience
인간 CD20 항원을 인식하는 2H7 클론 단일클론 항체로, Alexa Fluor 700 형광체가 결합되어 있습니다. Flow cytometry에 최적화되어 있으며, B세포 표지 및 활성화 연구에 활용됩니다. 고순도 친화 크로마토그래피 정제 및 안정적 액상 형태로 제공됩니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD20 Monoclonal Antibody (2H7), Alexa Fluor 700, eBioscience
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| Flow Cytometry (Flow) | 5 µL (0.06 µg)/test | View 13 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Rhesus monkey |
| Host / Isotype | Mouse / IgG2b, kappa |
| Recommended Isotype Control | Mouse IgG2b kappa Isotype Control (eBMG2b), Alexa Fluor™ 700 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H7 |
| Conjugate | Alexa Fluor™ 700 |
| Excitation / Emission Max | 696 / 719 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1963575 |
Additional Formats Available
- Unconjugated
- Alexa Fluor 532
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395, 496, 615, 737, 805
- Brilliant Violet 421, 605, 650, 711
- eFluor 450, 506
- FITC
- NovaFluor Blue 610-70S, 660-120S
- NovaFluor Red 710, 725
- NovaFluor Yellow 590, 660
- PE, PE-Cyanine5, PE-Cyanine5.5, PE-Cyanine7, PE-eFluor 610
- PerCP-Cyanine5.5
- Super Bright 436, 600, 645, 702, 780
- Request custom conjugation available
Product Specific Information
The 2H7 monoclonal antibody reacts with human CD20, a 33–36 kDa transmembrane protein expressed by developing and mature B cells but not plasma cells. CD20 may play a role in B-cell activation.
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-titrated for flow cytometry using normal human peripheral blood cells. Recommended use: 5 µL (0.06 µg) per test (100 µL final volume, 10⁵–10⁸ cells/test).
- Fluorochrome Information: Alexa Fluor® 700 emits at 723 nm, excited by red laser (633 nm). Use 685 LP mirror and 710/20 filter.
- Excitation/Emission: 633–647 nm / 723 nm
- Laser: Red Laser
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD20 is a non-glycosylated surface phosphoprotein (33–37 kDa) expressed on mature and most malignant B cells, a subpopulation of T lymphocytes, and follicular dendritic cells. It regulates calcium conductance, cell cycle, and B-cell proliferation. CD20 is associated with lipid rafts and serves as a therapeutic target for B-cell depletion in malignancies.
Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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