Thermo Fisher Scientific PCDH15 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human PCDH15 (NP_0011362351) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PCDH15,uniProtId:Q96QU1-1,ncbiNodeId:9606,antigenRange:160-400,antigenLength:1955,antigenImageFileName:PA5-116505_PCDH15_Q96QU1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116505_PCDH15_Q96QU1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901136

Product Specific Information

Positive Samples: SH-SY5Y, 293T, A-549, Raji, Mouse brain, Mouse liver, Mouse spleen, Rat brain, Rat liver

Immunogen sequence: TVNELTPVGT TIFTGFSGDN GATDIDDGPN GQIEYVIQYN PDDPTSNDTF EIPLMLTGNI VLRKRLNYED KTRYFVIIQA NDRAQNLNER RTTTTTLTVD VLDGDDLGPM FLPCVLVPNT RDCRPLTYQA AIPELRTPEE LNPIIVTPPI QAIDQDRNIQ PPSDRPGILY SILVGTPEDY PRFFHMHPRT AELSLLEPVN RDFHQKFDLV IKAEQDNGHP LPAFAGLHIE ILDENNQSPY F

Target Information

PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.