Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (LL002)
Cytokeratin 14 단백질을 표적하는 단클론 항체로, 인체·마우스·랫트 시료에 반응합니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능하며, 단백질 A/G로 정제된 액상 포맷입니다. 상피세포 및 편평세포암 연구용으로 적합합니다.
- 카탈로그번호
- 3861-MSM1-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (LL002)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | LL002 |
| Immunogen | A synthetic peptide of 15 amino acids from the C-terminus of human keratin 14 (residues 457–472). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, present in both keratinizing (e.g., skin) and non-keratinizing (e.g., mesothelial) tissues. Over 20 CKs have been identified and are classified into two groups:
- Type I (acidic polypeptides)
- Type II (basic polypeptides)
Keratin 14 (KRT14), a low molecular weight type I keratin, typically pairs with keratin 5. It serves as a marker to distinguish stratified epithelial cells from simple epithelial cells and is valuable in identifying squamous cell carcinomas. KRT14 is also considered a prognostic marker in breast carcinomas. In epithelial cells, at least one acidic and one basic keratin are co-expressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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