Thermo Fisher Scientific SMAD9 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SMAD9, suitable for WB and ICC/IF. Affinity-purified, unconjugated, and supplied in PBS with glycerol and BSA. Predicted cross-reactivity with monkey, dog, cat, and horse. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptides corresponding to Human SMAD9 (aa 159–173, 205–219) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633263 |
Product Specific Information
These polyclonal antibodies are of rabbit origin and developed by immunizing animals with proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in various research applications.
This product is for Research Use Only and is non-hazardous and non-infectious.
Predicted to react with Monkey, Dog, Cat, and Horse.
Target Information
SMAD proteins are members of the MAD-related family, essential components in the signaling pathways of serine/threonine kinase receptors of the transforming growth factor beta (TGF-β) superfamily.
They are classified as:
- Receptor-regulated SMADs (R-SMADs): SMAD1, 2, 5, 8, and 9
- Common-mediator SMAD (co-SMAD): SMAD4
- Inhibitory SMADs (I-SMADs): SMAD6 and 7
SMAD1, 5, 8, and 9 share high sequence homology, and antibodies may recognize common sequences among them. SMAD8 and SMAD9 are often used interchangeably in literature. Mutations in this gene can lead to pulmonary hypertension, primary 2 (PPH2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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