
Thermo Fisher Scientific Ly-108 Monoclonal Antibody (eBio13G3-19D (13G3-19D)), Biotin, eBioscience
Mouse Ly108 단백질을 인식하는 Biotin 결합 단클론 항체로, Flow Cytometry 및 Immunoprecipitation에 사용 가능. NK, T, B 세포 활성 연구에 적합하며, 0.5 mg/mL 농도의 액상 형태로 제공. 4°C에서 암소 보관, 동결 금지.
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Thermo Fisher Scientific Ly-108 Monoclonal Antibody (eBio13G3-19D (13G3-19D)), Biotin
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Flow Cytometry (Flow) | 1 µg/test | View publication |
| Immunoprecipitation (IP) | - | View publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Recommended Isotype Control | Mouse IgG2a kappa Isotype Control (eBM2a), Biotin, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBio13G3-19D (13G3-19D) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_763614 |
| Filtration | 0.2 µm post-manufacturing filtered |
Available Formats
- Unconjugated
- APC
- Functional Grade
- NovaFluor Blue 660-120S
- NovaFluor Red 685
- NovaFluor Red 700
- NovaFluor Red 755
- NovaFluor Yellow 610
- NovaFluor Yellow 660
- NovaFluor Yellow 700
- NovaFluor Yellow 755
- PE
- Request custom conjugation
Product Specific Information
The eBio13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108, also known as NTB-A, is expressed on NK, T, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and IFN-gamma expression, contributing to immune modulation.
CD4+ T cells from Ly108 knock-out mice exhibit reduced IL-4 production and defective neutrophil functions. Staining shows no strain differences between C57BL/6 and BALB/c mice; other strains have not been tested.
Applications Reported: Flow cytometric analysis.
Applications Tested: Tested by flow cytometric analysis of mouse splenocytes. Recommended ≤1 µg/test (final volume 100 µL). Optimal titration recommended for assay performance.
Target Information
Ly108 is the mouse homologue of human SLAMF6, expressed on NK, B, and T cells. Activation enhances NK cell activity and IFN-gamma expression.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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