Thermo Fisher Scientific ATG3 Recombinant Rabbit Monoclonal Antibody (23GB4330)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA552688 | - | Thermo Fisher Scientific MA552688 ATG3 Recombinant Rabbit Monoclonal Antibody (23GB4330) 100 uL pk | 재고문의 | pk | 0원 | - | 0원 | ||
MA552689 | - | Thermo Fisher Scientific MA552689 ATG3 Recombinant Rabbit Monoclonal Antibody (23GB4330) 20 uL pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000-1:5,000
Immunocytochemistry (ICC/IF)
1:1,000
Flow Cytometry (Flow)
1:2,000
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB4330
Immunogen
A synthesized peptide derived from human Apg3 (Atg3) (1-30AA). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
ATG3,
uniProtId:
Q9NT62-1,
ncbiNodeId:
9606,
antigenRange:
1-30,
antigenLength:
314,
antigenImageFileName:
MA5-52688_ATG3_Q9NT62-1_Rabbit.svg,
antigenImageFileNamePDP:
MA5-52688_ATG3_Q9NT62-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
ATG3 (APG3) is a widely expressed conjugating enzyme for APG8 lipidation, an essential step for the initiation of autophagy. Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. Autophagy is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG3 functions as an E2-like enzyme during the initial stages of autophagosome formation by catalyzing the formation of the Atg8-phosphatidylethanolamine (Atg8-PE) conjugate, which is critical for autophagy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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