Thermo Fisher Scientific Caspase 7 Polyclonal Antibody
Caspase-7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot 및 Immunohistochemistry에 적합. Human, Mouse, Rat 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
- 카탈로그번호
- PA520114
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the carboxy terminus of human Caspase-7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153725 |
Product Specific Information
- Suggested positive control: Human skeletal muscle tissue lysate
- PA5-20114 can be used with blocking peptide PEP-0232.
Target Information
Caspase 7 belongs to the cysteine protease family, divided into apoptotic and inflammatory subfamilies. Apoptotic caspases mediate programmed cell death, with initiator caspases activating executioner caspases such as Caspase 7. Caspase 7 was identified based on homology with Caspases 1 and 3 and C. elegans CED-3. Alternative splicing of Caspase-7 mRNA generates three distinct isoforms. Caspase-7 activity can be inhibited by XIAP expression. Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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