Thermo Fisher Scientific Caspase 7 Polyclonal Antibody
Caspase 7 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 냉장 보관(2–8°C) 권장, 장기 보관 시 -20°C.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide from near the amino-terminus of human Caspase-7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152696 |
Product Specific Information
- Suggested positive control: mouse skeletal muscle tissue lysate
- Compatible blocking peptide: PEP-0233
Target Information
Caspase 7 belongs to the family of cysteine proteases, which are categorized into apoptotic and inflammatory subfamilies.
Apoptotic caspases are involved in programmed cell death, while inflammatory caspases are associated with immune responses.
Caspase 7 functions as an executioner caspase activated by initiator caspases, leading to cleavage of cellular substrates during apoptosis.
It shares homology with caspases 1 and 3 and the C. elegans CED-3 protein.
Alternative splicing of Caspase-7 mRNA produces multiple isoforms.
Caspase-7 activity can be inhibited by XIAP expression.
Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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