
Thermo Fisher Scientific c-Fos Recombinant Rabbit Monoclonal Antibody (JJ0938)
Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능한 c-Fos 단백질 검출용 재조합 토끼 단일클론 항체. 높은 특이성과 민감도, 일관된 로트 간 품질, 동물 유래 성분 무첨가 포뮬레이션 제공.
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Thermo Fisher Scientific c-Fos Recombinant Rabbit Monoclonal Antibody (JJ0938)
Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ0938 |
| Immunogen | Synthetic peptide within Human c-Fos aa 231–268 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809769 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal production candidates.
Advantages include:
- 높은 특이성과 민감도
- 로트 간 일관성
- 동물 유래 성분 무첨가 포뮬레이션
- 다양한 표적에 대한 넓은 면역 반응성
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular proto-oncogene Fos (c-Fos), belongs to the fos transcription factor family and is encoded by the C-FOS gene on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates gene transcription involved in signal transduction, cell proliferation, and differentiation.
Phosphorylation occurs at multiple sites via stimuli such as growth factors and insulin. ERK MAPK is a major upstream kinase for phosphorylation at Threonine 232, influencing nuclear localization and transcriptional activity of c-Fos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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