Thermo Fisher Scientific NFS1 Polyclonal Antibody
Thermo Fisher Scientific NFS1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 Western blot, IHC, ICC/IF에 사용 가능합니다. 항원 친화 크로마토그래피로 정제된 고순도 (>95%) 항체로, NFS1 단백질 연구에 적합합니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Yeast |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human NFS1 (UniProt ID: Q9Y697-1, Antigen range: 1–457) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720711 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
NFS1 (nitrogen fixation 1), also known as NIFS or IscS (cysteine desulfurase), is a member of the class V pyridoxal-phosphate-dependent aminotransferase family.
It localizes to the cytoplasm or mitochondrion depending on cytosolic pH.
Highest expression levels are found in heart and skeletal muscle, with lower levels in liver, brain, and pancreas.
NFS1 catalyzes the removal of sulfur from cysteine to form alanine, supplying inorganic sulfur for iron-sulfur (Fe-S) clusters.
Fe-S clusters are essential cofactors in electron transfer, enzymatic catalysis, and DNA repair processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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