Thermo Fisher Scientific MXI1 Polyclonal Antibody
MXI1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간, 생쥐, 랫드에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 보관이 용이하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human MXI1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720707 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Myc regulation of cell proliferation and differentiation involves a family of related transcription factors. One such factor, Max, forms heterodimers with proteins such as Mad1, Mxi1, Mad3, and Mad4, leading to transcriptional repression. Both Myc and Mad proteins have short half-lives and are tightly regulated, while Max expression is constitutive and stable. Mammalian cDNAs encoding Mad-binding proteins (mSin3A and mSin3B) interact with Mad proteins through the PAH2 domain, suggesting that Mad-Max heterodimers repress transcription by tethering mSin3 to DNA as corepressors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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