Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI2F5), TrueMAB
TGIF1 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 최적화됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS 완충액 기반으로 보존제 없음. 연구용으로 TGIF 관련 신호전달 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F5 |
| Immunogen | Full length human recombinant TGIF1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TGIF (TG-interacting factor) belongs to the TALE (three-amino acid loop extension) superclass of homeodomain transcription factors. TALE homeobox proteins are conserved transcriptional regulators. TGIF binds to retinoid X receptor (RXR) responsive elements and acts as a transcriptional co-repressor of SMAD2. It may play a role in developmental and adult nuclear signaling. Mutations in TGIF1 are associated with holoprosencephaly type 4, a structural brain anomaly.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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