Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI4D10), TrueMAB
TGIF1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. 정제된 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 인간 TGIF1 풀랭스 단백질로 면역화된 항체로 연구용에 적합합니다. -20°C에서 보관하며 동결/해동 반복을 피해야 합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D10 |
| Immunogen | Full length human recombinant TGIF1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators.
This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter.
TGIF acts as a transcriptional co-repressor of SMAD2 and may be involved in nuclear signaling during development and adulthood.
Mutations in TGIF1 are associated with holoprosencephaly type 4, a structural anomaly of the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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