Thermo Fisher Scientific TGIF1 Monoclonal Antibody (OTI1H3), TrueMAB
인간 TGIF1 단백질을 인식하는 단클론 항체로 Western blot에 적합합니다. 정제된 IgG1 형태로 제공되며, 무보존제 PBS 완충액에 동결건조 상태로 공급됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H3 |
| Immunogen | Full length human recombinant protein of human TGIF1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TGIF is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This homeodomain binds to a retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. TGIF acts as a transcriptional co-repressor of SMAD2 and may participate in nuclear signal transmission during development and in adults. Mutations in this gene are associated with holoprosencephaly type 4, a structural anomaly of the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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