Thermo Fisher Scientific RORG Polyclonal Antibody
RORγ 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 사용 가능합니다. KLH-conjugated synthetic peptide를 면역원으로 제작되었으며, Protein A로 정제된 액상 형태입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human RORG, amino acids 415–518 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
RORγ (Retinoic acid-related Orphan Receptor gamma) is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily.
It functions as a ligand-activated transcription factor, essential for lymphoid organogenesis (lymph nodes and Peyer’s patches), and regulates apoptosis during thymopoiesis.
RORγ inhibits Fas ligand and IL2 expression and directs the differentiation of proinflammatory IL-17⁺ T helper cells.
It shares 50–51% sequence identity with RORA and RORB, and is 88% identical to mouse RORγ.
Expression is high in skeletal muscle and lower in other tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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