Thermo Fisher Scientific Phospho-BCAR1 (Tyr410) Polyclonal Antibody
Phospho-BCAR1 (Tyr410) 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Rabbit Polyclonal 형태입니다. 단백질 A로 정제되어 높은 특이성과 재현성을 제공합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr410 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The p130Cas (Crk-associated substrate, Cas) is a common cellular target of phosphorylation signaling via v-Crk and v-Src oncoproteins. It features an SH3 domain, multiple YXXP motifs, and a proline-rich region. p130Cas is involved in biological processes such as cell adhesion, migration, growth factor stimulation, cytokine receptor engagement, and bacterial infection. Physiological roles include cardiovascular development, actin filament assembly, and Src-induced cell transformation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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