Thermo Fisher Scientific XRCC1 Monoclonal Antibody (144)
Thermo Fisher Scientific의 XRCC1 Monoclonal Antibody (Clone 144)는 인간 XRCC1 단백질을 인식하는 마우스 IgG2a 항체입니다. Western blot, IHC, ICC, IP 등 다양한 응용에 적합하며, DNA 손상 복구 연구에 활용됩니다. 단백질 A 정제, 액상 형태로 4°C 보관됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:400 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 1 publication |
| Immunoprecipitation (IP) | 2 µg/mL | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 144 |
| Immunogen | Recombinant human XRCC1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| RRID | AB_1088326 |
Product Specific Information
A suggested positive control for this product is HT29, LS174T, HeLa cells or normal testis.
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that is physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III, and DNA polymerase beta. XRCC1 contains a BRCT domain (BRCA1 carboxyl terminus) that mediates protein-protein interactions with DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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