Thermo Fisher Scientific HSP60 Monoclonal Antibody (4B9/89), Alexa Fluor 555
HSP60 단백질을 인식하는 Alexa Fluor 555 결합 단클론 항체로, 인간, 마우스, 설치류 등 다양한 종에 반응합니다. Western blot 및 면역형광(ICC/IF)에 적합하며, 단백질 A로 정제된 액상 형태입니다. 4°C에서 암소 보관하며 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1–10 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B9/89 |
| Immunogen | Human placental HSP60 |
| Conjugate | Alexa Fluor™ 555 |
| Excitation / Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2662526 |
Available Formats
- Unconjugated (MA3-012)
- Alexa Fluor 488 (MA3-012-A488)
- Alexa Fluor 647 (MA3-012-A647)
- Request custom conjugation
Product Specific Information
The MA3012A555 antigen is human placental HSP60.
Epitope mapping studies using human HSP60 deletion mutants suggest that this antibody binds either between amino acids 335–366 or 484–547.
Target Information
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria.
This gene lies adjacent to a related family member, and the intergenic region functions as a bidirectional promoter. Several pseudogenes are associated with this gene. Two transcript variants encoding the same protein have been identified. Mutations in this gene are linked to autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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