Thermo Fisher Scientific HSP60 Monoclonal Antibody (4B9/89), Alexa Fluor 488
HSP60 단백질을 인식하는 Alexa Fluor 488 결합 단클론 항체로, 인간, 마우스, 설치류 등에 반응합니다. 면역형광 및 Western blot에 적합하며, 단백질 폴딩 연구에 활용됩니다. 4°C 암소 보관, 동결 금지.
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Applications
Western Blot (WB)
- Tested Dilution: Not specified
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–10 µg/mL
- View references
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B9/89 |
| Immunogen | Human placental HSP60 |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2663059 |
Additional Formats
- Unconjugated (MA3-012)
- Alexa Fluor 555 (MA3-012-A555)
- Alexa Fluor 647 (MA3-012-A647)
- Request custom conjugation
Product Specific Information
The MA3012A488 antigen is human placental HSP60. Epitope mapping studies using human HSP60 deletion mutants suggest that this antibody binds either between amino acids 335–366 or 484–547.
Target Information
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein functions as a signaling molecule in the innate immune system and is essential for folding and assembly of newly imported mitochondrial proteins. The gene lies adjacent to a related family member, with a bidirectional promoter between them. Several pseudogenes are associated with this gene, and two transcript variants encoding the same protein have been identified. Mutations in this gene cause autosomal recessive spastic paraplegia 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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