Thermo Fisher Scientific HSP60 Monoclonal Antibody (4B9/89), Alexa Fluor 488

Applications

Western Blot (WB)

• Tested Dilution: Not specified
• View 1 publication

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1–10 µg/mL
• View references

Product Specifications

Additional Formats

• Unconjugated (MA3-012)
• Alexa Fluor 555 (MA3-012-A555)
• Alexa Fluor 647 (MA3-012-A647)
• Request custom conjugation

Product Specific Information

The MA3012A488 antigen is human placental HSP60. Epitope mapping studies using human HSP60 deletion mutants suggest that this antibody binds either between amino acids 335–366 or 484–547.

Target Information

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein functions as a signaling molecule in the innate immune system and is essential for folding and assembly of newly imported mitochondrial proteins. The gene lies adjacent to a related family member, with a bidirectional promoter between them. Several pseudogenes are associated with this gene, and two transcript variants encoding the same protein have been identified. Mutations in this gene cause autosomal recessive spastic paraplegia 13.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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