Thermo Fisher Scientific CD79a Monoclonal Antibody (ZL7-4)

Applications

Product Specifications

Additional Formats

• FITC
• Request custom conjugation

Product Specific Information

MA1-81093 reacts with human CD79a-positive cells by flow cytometry and ELISA specific for a fusion protein of CD79a-Fc.
This clone has been reported to be useful in distinguishing B-CLL from mantle cell lymphoma in flow cytometric assays.

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Mouse anti-human CD79a antibody, clone ZL7-4 recognizes the human B-cell antigen receptor complex-associated protein alpha chain, also known as MB-1 membrane glycoprotein or CD79a.

Target Information

CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide.
It is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary for expression and function of the B-cell antigen receptor.
CD79a first appears at the pre-B cell stage and persists until the plasma cell stage, where it is found as an intracellular component.
It is expressed in most acute leukemias of precursor B cell type, B cell lines, B cell lymphomas, and some myelomas, but not in myeloid or T cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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