Thermo Fisher Scientific CD204 Monoclonal Antibody (2F8), FITC

Applications

Western Blot (WB)

• Tested Dilution: Not specified
• View 1 publication

Flow Cytometry (Flow)

• Tested Dilution: Neat
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Product Specifications

Available Formats

• Unconjugated (MA5-16492)
• Biotin (MA5-16493)
• PE (MA5-16496)
• Request custom conjugation

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Rat anti-Mouse CD204 antibody, clone 2F8 recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204.

Target Information

The CD204 gene encodes class A macrophage scavenger receptors, including three types (1, 2, 3) generated by alternative splicing.
These macrophage-specific trimeric integral membrane glycoproteins are involved in physiological and pathological processes such as atherosclerosis, Alzheimer’s disease, and host defense.

• Type 1 & 2: Functional receptors mediating endocytosis of modified LDLs.
• Type 3: Non-functional; trapped in the endoplasmic reticulum, inhibiting types 1 and 2 (dominant negative effect).
• Associated diseases: Barrett Esophagus, Prostate Cancer.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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