Thermo Fisher Scientific alpha-Actin-1 Polyclonal Antibody
Rabbit에서 생산된 Polyclonal 항체로, alpha-Actin-1 단백질을 인식합니다. Western Blot에 적합하며, 세포 골격 및 근육 수축 연구에 유용합니다. 합성 펩타이드(GQVITIGNERFR)-KLH 면역원 사용, 액상 형태로 제공되며 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1.0 µg/mL |
Publications: 2 publications available (Miscellaneous PubMed)
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide GQVITIGNERFRFR conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
Product Specific Information
If the antibody is provided in lyophilized form, reconstitute with deionized water (or equivalent) to achieve a concentration of 0.5 mg/mL.
Actin and myosin are two major cytoskeletal proteins involved in cell motility, secretion, cytoplasmic streaming, phagocytosis, and cytokinesis.
This Rabbit Anti-Alpha-Actin-1 Polyclonal Antibody was developed using a synthetic peptide conjugated to KLH.
Target Information
The gene encoding this protein belongs to the actin family, a group of highly conserved proteins essential for cell motility, structure, and integrity.
- Alpha actins: Major components of the contractile apparatus
- Beta and gamma actins: Regulate cell motility
Alpha-Actin-1 is specifically expressed in skeletal muscle.
Mutations in this gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions result in muscle fiber structural defects.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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