Thermo Fisher Scientific NFATC1 Polyclonal Antibody
NFATC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, Protein G로 정제된 액상 형태입니다. 면역반응 조절 관련 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:20 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids 264–282 (NKRKYSLNGRQPPYSPHHS) of human NFATC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2236020 |
Product Specific Information
Suggested positive control: antigen standard for NFATC1 (transient overexpression lysate).
Target Information
The NFATC1 gene encodes a component of the nuclear factor of activated T cells (NFAT) DNA-binding transcription complex. This complex includes a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. NFAT family transcription factors play a central role in inducible gene transcription during immune responses. NFATC1 acts as a major molecular target for immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified, which may regulate the inducible expression of different cytokine genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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