Thermo Fisher Scientific TTLL12 Polyclonal Antibody
TTLL12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 분석에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 정제 방식으로 높은 순도를 제공합니다. 암 연구 및 TTLL12 기능 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human TTLL12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720079 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein containing one TTL domain. Among the fourteen TTLL family members that modify tubulin, TTLL12 is the least characterized. It is highly expressed in metastatic prostate cancer cell lines and is considered a potential target for tumor therapy. Overexpression of TTLL12 may alter chromosome ploidy, while downregulation affects several post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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