Thermo Fisher Scientific Benzopyrene Monoclonal Antibody (BAP-13)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

The antibody BAP-13 is specific for Polynuclear Aromatic Hydrocarbon and inhibits DNA adduct formation. This property was investigated in rat liver microsomes spiked with calf thymus DNA and 7,8-diol-B[a]P.

Target Information

Benzo[a]pyrene, also known as 3,4-Benzopyrene or 3,4-BP, is a member of the Benzopyrenes—organic compounds containing a benzene fused to a pyrene (benzo[def]phenanthrene) ring system.
It is classified as a carcinogenic (IARC Group 1) and potentially toxic compound.
3,4-Benzpyrene is a crystalline, aromatic hydrocarbon consisting of five fused benzene rings and is formed during incomplete combustion of organic matter.

Common sources include:

• Gasoline and diesel exhaust
• Cigarette smoke
• Coal tar and coal tar pitch
• Charcoal-broiled foods
• Pyrolysis products of amino acids, fatty acids, and carbohydrates
• Soot, smoke, creosote oil, petroleum asphalt, and shale oils

This substance is used for research purposes only and is reasonably anticipated to be a human carcinogen.
(Source: National Center for Biotechnology Information, PubChem Compound Database; CID=2336)

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.