Thermo Fisher Scientific Phospho-M2 Muscarinic Acetylcholine Receptor (Ser286, Thr287, Ser288) Polyclonal Antibody
인산화된 M2 무스카린 아세틸콜린 수용체(Ser286, Thr287, Ser288)를 인식하는 폴리클로날 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human M2 around the phosphorylation site of Ser286/Thr287/Ser288. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor may also mediate smooth muscle contractility. In Alzheimer’s disease, selective loss of M2 subtype receptors occurs in cortical and hippocampal regions. Increased M2 receptor heterozygosity has been associated with depression in women. M2 receptors are expressed in various brain regions including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, as well as in lung and prostate tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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