Thermo Fisher Scientific Phospho-M2 Muscarinic Acetylcholine Receptor (Ser282, Ser283) Polyclonal Antibody
인간 M2 무스카린 아세틸콜린 수용체의 Ser282/Ser283 인산화 부위를 인식하는 폴리클로날 항체. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-M2 Muscarinic Acetylcholine Receptor (Ser282, Ser283) Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Publications: - [참고문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human M2 around the phosphorylation site of Ser282/Ser283 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor may also mediate smooth muscle contractility. Alzheimer’s disease involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain. Increased M2 receptor heterozygosity has been associated with depression in women. The M2 receptor is expressed in various regions of the brain including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, as well as in lung and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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