Thermo Fisher Scientific Phospho-M2 Muscarinic Acetylcholine Receptor (Ser315, Ser320) Polyclonal Antibody
Human CHRM2 단백질의 Ser315/Ser320 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western blot 검증 완료. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- 7TM0014F
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human M2 around the phosphorylation site of Ser315/Ser320 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor that functions as a presynaptic autoreceptor inhibiting acetylcholine release. The M2 receptor mediates smooth muscle contractility and is implicated in Alzheimer’s disease due to selective loss in cortical and hippocampal regions. Increased M2 receptor heterozygosity has been associated with depression in women. Expression has been reported in brain regions such as cerebellum, cerebral cortex, hippocampus, medulla, striatum, thalamus, and in lung and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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